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A Feasibility Study to Evaluate Bacillus subtilis as a Host for Producing Recombinant Human Parathyroid Hormone

BACKGROUND: Biosynthetic teriparatide (1–34) (TPD) is a N-terminally truncated version of human parathyroid hormone (hPTH). The recombinant form of this polypeptide has been expressed in Escherichia coli (E. coli) and approved as the first anabolic treatment of osteoporosis in the EU and the USA. Fe...

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Detalles Bibliográficos
Autores principales: Karimi, Mahdi, Behzadian, Farida, Rouhaninejad, Hamideh, Yari, Sanaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064005/
https://www.ncbi.nlm.nih.gov/pubmed/30090207