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Poly- and autoreactivity of HIV-1 bNAbs: implications for vaccine design
A central puzzle in HIV-1 research is the inability of vaccination or even infection to reliably elicit humoral responses against broadly neutralizing epitopes in the HIV-1 envelope protein. In infected individuals, broadly neutralizing antibodies (bNAbs) do arise in a substantial minority, but only...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064052/ https://www.ncbi.nlm.nih.gov/pubmed/30055635 http://dx.doi.org/10.1186/s12977-018-0435-0 |