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Knockdown of long non-coding RNA NEAT1 inhibits glioma cell migration and invasion via modulation of SOX2 targeted by miR-132

BACKGROUND: A better understanding of the molecular mechanism involving lncRNA-miRNA-mRNA network underlying glioma genesis is beneficial to the treatment of glioma. This study was designed to investigate the role of lncRNA NEAT1, miR-132 and SOX2 interaction in glioma. METHODS: Microarray analysis...

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Detalles Bibliográficos
Autores principales: Zhou, Ke, Zhang, Chi, Yao, Hui, Zhang, Xuewen, Zhou, Youxin, Che, Yanjun, Huang, Yulun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064054/
https://www.ncbi.nlm.nih.gov/pubmed/30053878
http://dx.doi.org/10.1186/s12943-018-0849-2