Construction of Lactobacillus casei ghosts by Holin-mediated inactivation and the potential as a safe and effective vehicle for the delivery of DNA vaccines

BACKGROUND: Bacterial ghosts (BGs) are empty bacterial cell envelopes generated by releasing the cellular contents. In this study, a phage infecting Lactobacillus casei ATCC 393 (L. casei 393) was isolated and designated Lcb. We aimed at using L. casei 393 as an antigen delivery system to express ph...

Descripción completa

Detalles Bibliográficos
Autores principales: Hou, Rui, Li, Muzi, Tang, Tingting, Wang, Ruichong, Li, Yijing, Xu, Yigang, Tang, Lijie, Wang, Li, Liu, Min, Jiang, Yanping, Cui, Wen, Qiao, Xinyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064150/
https://www.ncbi.nlm.nih.gov/pubmed/30055567
http://dx.doi.org/10.1186/s12866-018-1216-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064150/
https://www.ncbi.nlm.nih.gov/pubmed/30055567
http://dx.doi.org/10.1186/s12866-018-1216-6

Ejemplares similares