A dual role of miR-22 modulated by RelA/p65 in resensitizing fulvestrant-resistant breast cancer cells to fulvestrant by targeting FOXP1 and HDAC4 and constitutive acetylation of p53 at Lys382

Antiestrogen resistance is a major challenge encountered during the treatment of estrogen receptor alpha positive (ERα(+)) breast cancer. A better understanding of signaling pathways and downstream transcription factors and their targets may identify key molecules that can overcome antiestrogen resi...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Li, Dongping, Filkowski, Jody, Rodriguez-Juarez, Rocio, Storozynsky, Quinn, Malach, Megan, Carpenter, Emily, Kovalchuk, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064715/
https://www.ncbi.nlm.nih.gov/pubmed/30057418
http://dx.doi.org/10.1038/s41389-018-0063-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064715/
https://www.ncbi.nlm.nih.gov/pubmed/30057418
http://dx.doi.org/10.1038/s41389-018-0063-5

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