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Antigen-Specificity in the Thymic Development and Peripheral Activity of CD4(+)FOXP3(+) T Regulatory Cells
CD4(+)Foxp3(+) T regulatory cells (Treg) are essential for the life of the organism, in particular because they protect the host against its own autoaggressive CD4(+)Foxp3(−) T lymphocytes (Tconv). Treg distinctively suppress autoaggressive immunity while permitting efficient defense against infecti...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064734/ https://www.ncbi.nlm.nih.gov/pubmed/30083162 http://dx.doi.org/10.3389/fimmu.2018.01701 |