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Antigen-Specificity in the Thymic Development and Peripheral Activity of CD4(+)FOXP3(+) T Regulatory Cells

CD4(+)Foxp3(+) T regulatory cells (Treg) are essential for the life of the organism, in particular because they protect the host against its own autoaggressive CD4(+)Foxp3(−) T lymphocytes (Tconv). Treg distinctively suppress autoaggressive immunity while permitting efficient defense against infecti...

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Detalles Bibliográficos
Autores principales:	Pohar, Jelka, Simon, Quentin, Fillatreau, Simon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064734/ https://www.ncbi.nlm.nih.gov/pubmed/30083162 http://dx.doi.org/10.3389/fimmu.2018.01701

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