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Glucocorticoid-Induced Leucine Zipper Inhibits Interferon-Gamma Production in B Cells and Suppresses Colitis in Mice

Glucocorticoid-induced leucine zipper (GILZ) is transcriptionally upregulated by glucocorticoids (GCs) and mediates many of the anti-inflammatory effects of GCs. Since B cell activity has been linked to cytokine production and modulation of inflammatory responses, we herein investigated the role of...

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Detalles Bibliográficos
Autores principales: Bruscoli, Stefano, Sorcini, Daniele, Flamini, Sara, Gagliardi, Andrea, Adamo, Francesco, Ronchetti, Simona, Migliorati, Graziella, Bereshchenko, Oxana, Riccardi, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064738/
https://www.ncbi.nlm.nih.gov/pubmed/30083167
http://dx.doi.org/10.3389/fimmu.2018.01720