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Studying Spatial Protein Quality Control, Proteopathies, and Aging Using Different Model Misfolding Proteins in S. cerevisiae

Protein quality control (PQC) is critical to maintain a functioning proteome. Misfolded or toxic proteins are either refolded or degraded by a system of temporal quality control and can also be sequestered into aggregates or inclusions by a system of spatial quality control. Breakdown of this concer...

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Detalles Bibliográficos
Autores principales: Schneider, Kara L., Nyström, Thomas, Widlund, Per O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064742/
https://www.ncbi.nlm.nih.gov/pubmed/30083092
http://dx.doi.org/10.3389/fnmol.2018.00249