Sphingosine 1 phosphate receptor-1 (S1PR1) signaling protects cardiac function by inhibiting cardiomyocyte autophagy

OBJECTIVE: To investigate the role of sphingosine-1-phosphate (S1P) and its receptors in cardiomyocyte autophagy, cardiomyocyte hypertrophy and cardiac function. METHODS: Cardiomyocytes were isolated from neonatal Vista rats. Autophagy and hypertrophy of cardiomyocytes were induced via starvation cu...

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Detalles Bibliográficos
Autores principales: Chen, Yong–Zeng, Wang, Fan, Wang, Hai–Jun, Liu, Hong–Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064777/
https://www.ncbi.nlm.nih.gov/pubmed/30083186
http://dx.doi.org/10.11909/j.issn.1671-5411.2018.05.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064777/
https://www.ncbi.nlm.nih.gov/pubmed/30083186
http://dx.doi.org/10.11909/j.issn.1671-5411.2018.05.003

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