Allergen Delivery Inhibitors: A Rationale for Targeting Sentinel Innate Immune Signaling of Group 1 House Dust Mite Allergens through Structure-Based Protease Inhibitor Design

Diverse evidence from epidemiologic surveys and investigations into the molecular basis of allergenicity have revealed that a small cadre of “initiator” allergens promote the development of allergic diseases, such as asthma, allergic rhinitis, and atopic dermatitis. Pre-eminent among these initiator...

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Detalles Bibliográficos
Autores principales: Zhang, Jihui, Chen, Jie, Newton, Gary K., Perrior, Trevor R., Robinson, Clive
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2018
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064784/
https://www.ncbi.nlm.nih.gov/pubmed/29976563
http://dx.doi.org/10.1124/mol.118.112730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064784/
https://www.ncbi.nlm.nih.gov/pubmed/29976563
http://dx.doi.org/10.1124/mol.118.112730

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