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Quantitative imaging mass spectroscopy reveals roles of heme oxygenase-2 for protecting against transhemispheric diaschisis in the brain ischemia

Carbon monoxide-generating heme oxygenase-2 is expressed in neurons and plays a crucial role for regulating hypoxic vasodilation through mechanisms unlocking carbon monoxide-dependent inhibition of H(2)S-generating cystathionine β-synthase expressed in astrocytes. This study aims to examine whether...

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Detalles Bibliográficos
Autores principales: Goto, Shinichi, Morikawa, Takayuki, Kubo, Akiko, Takubo, Keiyo, Fukuda, Keiichi, Kajimura, Mayumi, Suematsu, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064818/
https://www.ncbi.nlm.nih.gov/pubmed/30087547
http://dx.doi.org/10.3164/jcbn.17-136