Tumor Killing by CD4(+) T Cells Is Mediated via Induction of Inducible Nitric Oxide Synthase-Dependent Macrophage Cytotoxicity

CD4(+) T cells can induce potent anti-tumor immune responses. Due to the lack of MHC class II expression in most cancer cells, antigen recognition occurs indirectly via uptake and presentation on tumor-infiltrating antigen-presenting cells (APCs). Activation of the APCs can induce tumor rejection, b...

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Detalles Bibliográficos
Autores principales: Fauskanger, Marte, Haabeth, Ole Audun Werner, Skjeldal, Frode Miltzow, Bogen, Bjarne, Tveita, Anders Aune
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064871/
https://www.ncbi.nlm.nih.gov/pubmed/30083157
http://dx.doi.org/10.3389/fimmu.2018.01684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064871/
https://www.ncbi.nlm.nih.gov/pubmed/30083157
http://dx.doi.org/10.3389/fimmu.2018.01684

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