Size Matters: Ryanodine Receptor Cluster Size Affects Arrhythmogenic Sarcoplasmic Reticulum Calcium Release

BACKGROUND: Ryanodine receptors (RyR) mediate sarcoplasmic reticulum calcium (Ca(2+)) release and influence myocyte Ca(2+) homeostasis and arrhythmias. In cardiac myocytes, RyRs are found in clusters of various sizes and shapes, and RyR cluster size may critically influence normal and arrhythmogenic...

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Detalles Bibliográficos
Autores principales: Galice, Samuel, Xie, Yuanfang, Yang, Yi, Sato, Daisuke, Bers, Donald M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064922/
https://www.ncbi.nlm.nih.gov/pubmed/29929992
http://dx.doi.org/10.1161/JAHA.118.008724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064922/
https://www.ncbi.nlm.nih.gov/pubmed/29929992
http://dx.doi.org/10.1161/JAHA.118.008724

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