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Size Matters: Ryanodine Receptor Cluster Size Affects Arrhythmogenic Sarcoplasmic Reticulum Calcium Release
BACKGROUND: Ryanodine receptors (RyR) mediate sarcoplasmic reticulum calcium (Ca(2+)) release and influence myocyte Ca(2+) homeostasis and arrhythmias. In cardiac myocytes, RyRs are found in clusters of various sizes and shapes, and RyR cluster size may critically influence normal and arrhythmogenic...
Autores principales: | Galice, Samuel, Xie, Yuanfang, Yang, Yi, Sato, Daisuke, Bers, Donald M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064922/ https://www.ncbi.nlm.nih.gov/pubmed/29929992 http://dx.doi.org/10.1161/JAHA.118.008724 |
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