Growth Differentiation Factor 5 Improves Neurogenesis and Functional Recovery in Adult Mouse Hippocampus Following Traumatic Brain Injury

The aim of this study was to investigate the therapeutic effect of growth differentiation factor 5 (GDF-5) on traumatic brain injury (TBI) in mice. We utilized a controlled cortical impact to establish a mouse TBI model, and then stereotaxically administered 25 or 100 ng GDF-5 into the bilateral hip...

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Detalles Bibliográficos
Autores principales: Wu, Hongjie, Li, Jing, Xu, Dongxiao, Zhang, Qiansheng, Cui, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064945/
https://www.ncbi.nlm.nih.gov/pubmed/30083129
http://dx.doi.org/10.3389/fneur.2018.00592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064945/
https://www.ncbi.nlm.nih.gov/pubmed/30083129
http://dx.doi.org/10.3389/fneur.2018.00592

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