Superinfection and cure of infected cells as mechanisms for hepatitis C virus adaptation and persistence

RNA viruses exist as a genetically diverse quasispecies with extraordinary ability to adapt to abrupt changes in the host environment. However, the molecular mechanisms that contribute to their rapid adaptation and persistence in vivo are not well studied. Here, we probe hepatitis C virus (HCV) pers...

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Detalles Bibliográficos
Autores principales: Ke, Ruian, Li, Hui, Wang, Shuyi, Ding, Wenge, Ribeiro, Ruy M., Giorgi, Elena E., Bhattacharya, Tanmoy, Barnard, Richard J. O., Hahn, Beatrice H., Shaw, George M., Perelson, Alan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065014/
https://www.ncbi.nlm.nih.gov/pubmed/29987026
http://dx.doi.org/10.1073/pnas.1805267115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065014/
https://www.ncbi.nlm.nih.gov/pubmed/29987026
http://dx.doi.org/10.1073/pnas.1805267115

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