Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle

Circadian misalignment, such as in shift work, has been associated with obesity and type 2 diabetes. However, direct effects of circadian misalignment on skeletal muscle insulin sensitivity and the muscle molecular circadian clock have never been studied in humans. Here, we investigated insulin sens...

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Detalles Bibliográficos
Autores principales: Wefers, Jakob, van Moorsel, Dirk, Hansen, Jan, Connell, Niels J., Havekes, Bas, Hoeks, Joris, van Marken Lichtenbelt, Wouter D., Duez, Hélène, Phielix, Esther, Kalsbeek, Andries, Boekschoten, Mark V., Hooiveld, Guido J., Hesselink, Matthijs K. C., Kersten, Sander, Staels, Bart, Scheer, Frank A. J. L., Schrauwen, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065021/
https://www.ncbi.nlm.nih.gov/pubmed/29987027
http://dx.doi.org/10.1073/pnas.1722295115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065021/
https://www.ncbi.nlm.nih.gov/pubmed/29987027
http://dx.doi.org/10.1073/pnas.1722295115

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