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Positional specificity of different transcription factor classes within enhancers
Gene expression is controlled by sequence-specific transcription factors (TFs), which bind to regulatory sequences in DNA. TF binding occurs in nucleosome-depleted regions of DNA (NDRs), which generally encompass regions with lengths similar to those protected by nucleosomes. However, less is known...
Autores principales: | Grossman, Sharon R., Engreitz, Jesse, Ray, John P., Nguyen, Tung H., Hacohen, Nir, Lander, Eric S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065035/ https://www.ncbi.nlm.nih.gov/pubmed/29987030 http://dx.doi.org/10.1073/pnas.1804663115 |
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