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Integrative analysis of single-cell genomics data by coupled nonnegative matrix factorizations

When different types of functional genomics data are generated on single cells from different samples of cells from the same heterogeneous population, the clustering of cells in the different samples should be coupled. We formulate this “coupled clustering” problem as an optimization problem and pro...

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Detalles Bibliográficos
Autores principales: Duren, Zhana, Chen, Xi, Zamanighomi, Mahdi, Zeng, Wanwen, Satpathy, Ansuman T., Chang, Howard Y., Wang, Yong, Wong, Wing Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065048/
https://www.ncbi.nlm.nih.gov/pubmed/29987051
http://dx.doi.org/10.1073/pnas.1805681115