Cargando…

Histone demethylase KDM4D promotes gastrointestinal stromal tumor progression through HIF1β/VEGFA signalling

BACKGROUND: Gastrointestinal stromal tumour (GIST) is the most common soft tissue sarcoma. The identification of the molecular mechanisms regulating GIST progression is vital for its treatment and prevention. Increasing reports have demonstrated that epigenetic alterations play critical roles in GIS...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Fuqing, Li, Haijie, Liu, Lu, Xu, Feng, Lai, Senyan, Luo, Xuelai, Hu, Junbo, Yang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065154/
https://www.ncbi.nlm.nih.gov/pubmed/30060750
http://dx.doi.org/10.1186/s12943-018-0861-6