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Subcellular localization of alpha-synuclein aggregates and their interaction with membranes

For more than a decade numerous evidence has been reported on the mechanisms of toxicity of α-synuclein (αS) oligomers and aggregates in α-synucleinopathies. These species were thought to form freely in the cytoplasm but recent reports of αS multimer conformations when bound to synaptic vesicles in...

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Detalles Bibliográficos
Autores principales: Miraglia, Fabiana, Ricci, Alessio, Rota, Lucia, Colla, Emanuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065224/
https://www.ncbi.nlm.nih.gov/pubmed/30028312
http://dx.doi.org/10.4103/1673-5374.235013