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What can computational modeling offer for studying the Ca(2+) dysregulation in Alzheimer's disease: current research and future directions
Ca(2+) dysregulation is an early event observed in Alzheimer’s disease (AD) patients preceding the presence of its clinical symptoms. Dysregulation of neuronal Ca(2+) will cause synaptic loss and neuronal death, eventually leading to memory impairments and cognitive decline. Treatments targeting Ca(...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065234/ https://www.ncbi.nlm.nih.gov/pubmed/30028315 http://dx.doi.org/10.4103/1673-5374.235020 |