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Characterization of the immune response elicited by the vaccinia virus L3 protein delivered as naked DNA

Poxviruses are complex dsDNA viruses with over 200 genes, many of them with unknown role in the stimulation of immune responses. Among these, the vaccinia virus (VACV) L3L ORF encodes an essential protein for the transcription of the VACV early genes. To the best of our knowledge, the immune respons...

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Detalles Bibliográficos
Autores principales: Ramírez, Maite, Santos, Saritza, Martínez, Osmarie, Rodríguez, Ricardo, Miranda, Eric, Ramos-Perez, Willy D., Otero, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065253/
https://www.ncbi.nlm.nih.gov/pubmed/29525282
http://dx.doi.org/10.1016/j.vaccine.2018.02.033