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Aberrant Protein Turn-Over Associated With Myofibrillar Disorganization in FHL1 Knockout Mice
Mutations in the FHL1 gene, and FHL1 protein deletion, are associated with rare hereditary myopathies and cardiomyopathies. FHL1-null mice develop age-dependent myopathy and increased autophagic activity. However, the molecular pathway involved in contractile function and increased autophagic activi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065255/ https://www.ncbi.nlm.nih.gov/pubmed/30083183 http://dx.doi.org/10.3389/fgene.2018.00273 |