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In vivo targeted single-nucleotide editing in zebrafish

To date, several genome editing technologies have been developed and are widely utilized in many fields of biology. Most of these technologies, if not all, use nucleases to create DNA double-strand breaks (DSBs), raising the potential risk of cell death and/or oncogenic transformation. The risks hin...

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Detalles Bibliográficos
Autores principales: Tanaka, Shingo, Yoshioka, Shin, Nishida, Keiji, Hosokawa, Hiroshi, Kakizuka, Akira, Maegawa, Shingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065354/
https://www.ncbi.nlm.nih.gov/pubmed/30061715
http://dx.doi.org/10.1038/s41598-018-29794-9