Droplet digital PCR shows the D-Loop to be an error prone locus for mitochondrial DNA copy number determination

Absolute quantification of mitochondrial DNA copy number (mCN) provides important insights in many fields of research including cancer, cardiovascular and reproductive health. Droplet digital PCR (ddPCR) natively reports absolute copy number, and we have developed a single-dye, multiplex assay to me...

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Detalles Bibliográficos
Autores principales: Li, Brian, Kaushik, Sonal, Kalinowski, Pola, Kim, BaRun, Gershome, Cynthia, Ching, Joyce, Poburko, Damon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065360/
https://www.ncbi.nlm.nih.gov/pubmed/30061621
http://dx.doi.org/10.1038/s41598-018-29621-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065360/
https://www.ncbi.nlm.nih.gov/pubmed/30061621
http://dx.doi.org/10.1038/s41598-018-29621-1

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