Overexpression of endophilin A1 exacerbates synaptic alterations in a mouse model of Alzheimer’s disease

Endophilin A1 (EP) is a protein enriched in synaptic terminals that has been linked to Alzheimer’s disease (AD). Previous in vitro studies have shown that EP can bind to a variety of proteins, which elicit changes in synaptic transmission of neurotransmitters and spine formation. Additionally, we pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Qing, Wang, Yongfu, Du, Fang, Yan, Shijun, Hu, Gang, Origlia, Nicola, Rutigliano, Grazia, Sun, Qinru, Yu, Haiyang, Ainge, James, Yan, Shi Fang, Gunn-Moore, Frank, Yan, Shirley ShiDu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065365/
https://www.ncbi.nlm.nih.gov/pubmed/30061577
http://dx.doi.org/10.1038/s41467-018-04389-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065365/
https://www.ncbi.nlm.nih.gov/pubmed/30061577
http://dx.doi.org/10.1038/s41467-018-04389-0

Ejemplares similares