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Overexpression of endophilin A1 exacerbates synaptic alterations in a mouse model of Alzheimer’s disease

Endophilin A1 (EP) is a protein enriched in synaptic terminals that has been linked to Alzheimer’s disease (AD). Previous in vitro studies have shown that EP can bind to a variety of proteins, which elicit changes in synaptic transmission of neurotransmitters and spine formation. Additionally, we pr...

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Detalles Bibliográficos
Autores principales:	Yu, Qing, Wang, Yongfu, Du, Fang, Yan, Shijun, Hu, Gang, Origlia, Nicola, Rutigliano, Grazia, Sun, Qinru, Yu, Haiyang, Ainge, James, Yan, Shi Fang, Gunn-Moore, Frank, Yan, Shirley ShiDu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065365/ https://www.ncbi.nlm.nih.gov/pubmed/30061577 http://dx.doi.org/10.1038/s41467-018-04389-0

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