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Statistical mechanics for metabolic networks during steady state growth

Which properties of metabolic networks can be derived solely from stoichiometry? Predictive results have been obtained by flux balance analysis (FBA), by postulating that cells set metabolic fluxes to maximize growth rate. Here we consider a generalization of FBA to single-cell level using maximum e...

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Detalles Bibliográficos
Autores principales: De Martino, Daniele, MC Andersson, Anna, Bergmiller, Tobias, Guet, Călin C., Tkačik, Gašper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065372/
https://www.ncbi.nlm.nih.gov/pubmed/30061556
http://dx.doi.org/10.1038/s41467-018-05417-9