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Arthropod transcriptional activator protein-1 (AP-1) aids tick-rickettsial pathogen survival in the cold

Ixodes scapularis ticks transmit several pathogens to humans including rickettsial bacterium, Anaplasma phagocytophilum. Here, we report that A. phagocytophilum uses tick transcriptional activator protein-1 (AP-1) as a molecular switch in the regulation of arthropod antifreeze gene, iafgp. RNAi-medi...

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Detalles Bibliográficos
Autores principales: Khanal, Supreet, Taank, Vikas, Anderson, John F., Sultana, Hameeda, Neelakanta, Girish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065373/
https://www.ncbi.nlm.nih.gov/pubmed/30061607
http://dx.doi.org/10.1038/s41598-018-29654-6