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Explaining cancer type specific mutations with transcriptomic and epigenomic features in normal tissues
Most cancer driver genes are involved in generic cellular processes such as DNA repair, cell proliferation and cell adhesion, yet their mutations are often confined to specific cancer types. To resolve this paradox, we explained mutation frequencies of selected genes across tumor types with four fea...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065413/ https://www.ncbi.nlm.nih.gov/pubmed/30061703 http://dx.doi.org/10.1038/s41598-018-29861-1 |