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Loss of profilin 2 contributes to enhanced epithelial-mesenchymal transition and metastasis of colorectal cancer

Profilin 2 (PFN2) functions as an actin cytoskeleton regulator and serves an important role in cell motility. However, a role for PFN2 in the progression of colorectal cancer (CRC), particularly in metastasis, has yet to be clarified. The aim of the present study was to investigate whether PFN2 serv...

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Detalles Bibliográficos
Autores principales: Zhang, Hui, Yang, Weiqiang, Yan, Jinlong, Zhou, Kaiping, Wan, Boshun, Shi, Peidong, Chen, Yueyu, He, Songbing, Li, Dechun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065425/
https://www.ncbi.nlm.nih.gov/pubmed/30015842
http://dx.doi.org/10.3892/ijo.2018.4475