Liposomal paclitaxel induces fewer hematopoietic and cardiovascular complications than bioequivalent doses of Taxol

Paclitaxel (PTX) exhibits potent antineoplastic activity against various human malignancies; however, clinical application must overcome the inherent hydrophobicity of this molecule. The commercialized Taxol formulation utilizes Cremophor EL (CrEL)/ethanol as a solvent to stabilize and dispense PTX...

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Detalles Bibliográficos
Autores principales: Huang, Shih-Ting, Wang, Yi-Ping, Chen, Yen-Hui, Lin, Chin-Tarng, Li, Wen-Shan, Wu, Han-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065427/
https://www.ncbi.nlm.nih.gov/pubmed/29956746
http://dx.doi.org/10.3892/ijo.2018.4449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065427/
https://www.ncbi.nlm.nih.gov/pubmed/29956746
http://dx.doi.org/10.3892/ijo.2018.4449

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