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Deoxycholic acid supplementation impairs glucose homeostasis in mice

Bile acids are critical contributors to the regulation of whole body glucose homeostasis; however, the mechanisms remain incompletely defined. While the hydrophilic bile acid subtype, ursodeoxycholic acid, has been shown to attenuate hepatic endoplasmic reticulum (ER) stress and thereby improve gluc...

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Detalles Bibliográficos
Autores principales: Zaborska, Karolina E., Lee, Seon A., Garribay, Darline, Cha, Eumee, Cummings, Bethany P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066200/
https://www.ncbi.nlm.nih.gov/pubmed/30059528
http://dx.doi.org/10.1371/journal.pone.0200908