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MiR-145 expression and rare NOTCH1 variants in bicuspid aortic valve-associated aortopathy

MicroRNAs (miRNAs) may serve as elegant tool to improve risk stratification in bicuspid aortic valve (BAV)-associated aortopathy. However, the exact pathogenetic pathway by which miRNAs impact aortopathy progression is unknown. Herewith, we aimed to analyze the association between circulating miRNAs...

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Detalles Bibliográficos
Autores principales: Girdauskas, Evaldas, Petersen, Johannes, Neumann, Niklas, Ungelenk, Martin, Kurth, Ingo, Reichenspurner, Hermann, Zeller, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066209/
https://www.ncbi.nlm.nih.gov/pubmed/30059548
http://dx.doi.org/10.1371/journal.pone.0200205