An RNA-Binding Multimer Specifies Nematode Sperm Fate

FOG-3 is a master regulator of sperm fate in Caenorhabditis elegans and homologous to Tob/BTG proteins, which in mammals are monomeric adaptors that recruit enzymes to RNA binding proteins. Here, we determine the FOG-3 crystal structure and in vitro demonstrate that FOG-3 forms dimers that can multi...

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Detalles Bibliográficos
Autores principales: Aoki, Scott T., Porter, Douglas F., Prasad, Aman, Wickens, Marvin, Bingman, Craig A., Kimble, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066285/
https://www.ncbi.nlm.nih.gov/pubmed/29949762
http://dx.doi.org/10.1016/j.celrep.2018.05.095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066285/
https://www.ncbi.nlm.nih.gov/pubmed/29949762
http://dx.doi.org/10.1016/j.celrep.2018.05.095

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