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Clinical outcomes of prolonged infusion (extended infusion or continuous infusion) versus intermittent bolus of meropenem in severe infection: A meta-analysis

BACKGROUND: Meropenem exhibits time-dependent antimicrobial activity and prolonged infusion (PI) (extended infusion or continuous infusion, EI or CI) of meropenem can better achieve pharmacodynamics target when comparing with intermittent bolus (IB). However, the clinical outcomes between two groups...

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Detalles Bibliográficos
Autores principales: Yu, Zhenwei, Pang, Xiaoping, Wu, Xuqi, Shan, Chunlei, Jiang, Saiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066326/
https://www.ncbi.nlm.nih.gov/pubmed/30059536
http://dx.doi.org/10.1371/journal.pone.0201667