Adaptation to constant light requires Fic-mediated AMPylation of BiP to protect against reversible photoreceptor degeneration

In response to environmental, developmental, and pathological stressors, cells engage homeostatic pathways to maintain their function. Among these pathways, the Unfolded Protein Response protects cells from the accumulation of misfolded proteins in the ER. Depending on ER stress levels, the ER-resid...

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Detalles Bibliográficos
Autores principales: Moehlman, Andrew T, Casey, Amanda K, Servage, Kelly, Orth, Kim, Krämer, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066327/
https://www.ncbi.nlm.nih.gov/pubmed/30015618
http://dx.doi.org/10.7554/eLife.38752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066327/
https://www.ncbi.nlm.nih.gov/pubmed/30015618
http://dx.doi.org/10.7554/eLife.38752

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