Genome-Scale Oscillations in DNA Methylation during Exit from Pluripotency

Pluripotency is accompanied by the erasure of parental epigenetic memory, with naïve pluripotent cells exhibiting global DNA hypomethylation both in vitro and in vivo. Exit from pluripotency and priming for differentiation into somatic lineages is associated with genome-wide de novo DNA methylation....

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Detalles Bibliográficos
Autores principales: Rulands, Steffen, Lee, Heather J., Clark, Stephen J., Angermueller, Christof, Smallwood, Sébastien A., Krueger, Felix, Mohammed, Hisham, Dean, Wendy, Nichols, Jennifer, Rugg-Gunn, Peter, Kelsey, Gavin, Stegle, Oliver, Simons, Benjamin D., Reik, Wolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066359/
https://www.ncbi.nlm.nih.gov/pubmed/30031774
http://dx.doi.org/10.1016/j.cels.2018.06.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066359/
https://www.ncbi.nlm.nih.gov/pubmed/30031774
http://dx.doi.org/10.1016/j.cels.2018.06.012

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