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High expression of HMGA2 independently predicts poor clinical outcomes in acute myeloid leukemia

In acute myeloid leukemia (AML), risk stratification based on cytogenetics and mutation profiling is essential but remains insufficient to select the optimal therapy. Accurate biomarkers are needed to improve prognostic assessment. We analyzed RNA sequencing and survival data of 430 AML patients and...

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Detalles Bibliográficos
Autores principales: Marquis, Miriam, Beaubois, Cyrielle, Lavallée, Vincent-Philippe, Abrahamowicz, Michal, Danieli, Coraline, Lemieux, Sébastien, Ahmad, Imran, Wei, Andrew, Ting, Stephen B., Fleming, Shaun, Schwarer, Anthony, Grimwade, David, Grey, William, Hills, Robert K., Vyas, Paresh, Russell, Nigel, Sauvageau, Guy, Hébert, Josée
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066481/
https://www.ncbi.nlm.nih.gov/pubmed/30061630
http://dx.doi.org/10.1038/s41408-018-0103-6