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CRISPR/Cas9-Based Editing of Streptomyces for Discovery, Characterization, and Production of Natural Products

Microbial natural products (NPs) especially of the Streptomyces genus have been regarded as an unparalleled resource for pharmaceutical drugs discovery. Moreover, recent progress in sequencing technologies and computational resources further reinforces to identify numerous NP biosynthetic gene clust...

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Detalles Bibliográficos
Autores principales: Tao, Weixin, Yang, Anna, Deng, Zixin, Sun, Yuhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066502/
https://www.ncbi.nlm.nih.gov/pubmed/30087666
http://dx.doi.org/10.3389/fmicb.2018.01660