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Lactobacillus rhamnosus GR-1 Ameliorates Escherichia coli-Induced Activation of NLRP3 and NLRC4 Inflammasomes With Differential Requirement for ASC

Escherichia coli is a common cause of mastitis in dairy cows. The adaptor protein apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) synergizes with caspase-1 to regulate inflammasome activation during pathogen infection. Here, the ASC gene was knocked out in bovin...

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Detalles Bibliográficos
Autores principales: Wu, Qiong, Zhu, Yao-Hong, Xu, Jin, Liu, Xiao, Duan, Cong, Wang, Mei-Jun, Wang, Jiu-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066506/
https://www.ncbi.nlm.nih.gov/pubmed/30087667
http://dx.doi.org/10.3389/fmicb.2018.01661