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Lactobacillus rhamnosus GR-1 Ameliorates Escherichia coli-Induced Activation of NLRP3 and NLRC4 Inflammasomes With Differential Requirement for ASC
Escherichia coli is a common cause of mastitis in dairy cows. The adaptor protein apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) synergizes with caspase-1 to regulate inflammasome activation during pathogen infection. Here, the ASC gene was knocked out in bovin...
Autores principales: | Wu, Qiong, Zhu, Yao-Hong, Xu, Jin, Liu, Xiao, Duan, Cong, Wang, Mei-Jun, Wang, Jiu-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066506/ https://www.ncbi.nlm.nih.gov/pubmed/30087667 http://dx.doi.org/10.3389/fmicb.2018.01661 |
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