Homology Modeling Informs Ligand Discovery for the Glutamine Transporter ASCT2

The Alanine-Serine-Cysteine transporter (SLC1A5, ASCT2), is a neutral amino acid exchanger involved in the intracellular homeostasis of amino acids in peripheral tissues. Given its role in supplying glutamine to rapidly proliferating cancer cells in several tumor types such as triple-negative breast...

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Detalles Bibliográficos
Autores principales: Garibsingh, Rachel-Ann A., Otte, Nicholas J., Ndaru, Elias, Colas, Claire, Grewer, Christof, Holst, Jeff, Schlessinger, Avner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066518/
https://www.ncbi.nlm.nih.gov/pubmed/30137742
http://dx.doi.org/10.3389/fchem.2018.00279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066518/
https://www.ncbi.nlm.nih.gov/pubmed/30137742
http://dx.doi.org/10.3389/fchem.2018.00279

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