Tyrosine Kinase Signaling in Cancer Metabolism: PKM2 Paradox in the Warburg Effect

The Warburg Effect, or aerobic glycolysis, is one of the major metabolic alterations observed in cancer. Hypothesized to increase a cell's proliferative capacity via regenerating NAD(+), increasing the pool of glycolytic biosynthetic intermediates, and increasing lactate production that affects...

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Detalles Bibliográficos
Autores principales: Wiese, Elizabeth K., Hitosugi, Taro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066570/
https://www.ncbi.nlm.nih.gov/pubmed/30087897
http://dx.doi.org/10.3389/fcell.2018.00079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066570/
https://www.ncbi.nlm.nih.gov/pubmed/30087897
http://dx.doi.org/10.3389/fcell.2018.00079

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