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Tyrosine Kinase Signaling in Cancer Metabolism: PKM2 Paradox in the Warburg Effect
The Warburg Effect, or aerobic glycolysis, is one of the major metabolic alterations observed in cancer. Hypothesized to increase a cell's proliferative capacity via regenerating NAD(+), increasing the pool of glycolytic biosynthetic intermediates, and increasing lactate production that affects...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066570/ https://www.ncbi.nlm.nih.gov/pubmed/30087897 http://dx.doi.org/10.3389/fcell.2018.00079 |