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First evaluation of PET-based human biodistribution and radiation dosimetry of (11)C-BU99008, a tracer for imaging the imidazoline(2) binding site

BACKGROUND: We measured whole body distribution of (11)C-BU99008, a new PET biomarker for non-invasive identification of the imidazoline(2) binding site. The purpose of this phase I study was to evaluate the biodistribution and radiation dosimetry of (11)C-BU99008 in healthy human subjects. METHODS:...

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Detalles Bibliográficos
Autores principales: Venkataraman, Ashwin V., Keat, Nicholas, Myers, James F., Turton, Samuel, Mick, Inge, Gunn, Roger N., Rabiner, Eugenii A., Passchier, Jan, Parker, Christine A., Tyacke, Robin J., Nutt, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066589/
https://www.ncbi.nlm.nih.gov/pubmed/30062395
http://dx.doi.org/10.1186/s13550-018-0429-x