GATA2 Is Dispensable for Specification of Hemogenic Endothelium but Promotes Endothelial-to-Hematopoietic Transition

The transcriptional factor GATA2 is required for blood and hematopoietic stem cell formation during the hemogenic endothelium (HE) stage of development in the embryo. However, it is unclear if GATA2 controls HE lineage specification or if it solely regulates endothelial-to-hematopoietic transition (...

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Detalles Bibliográficos
Autores principales: Kang, HyunJun, Mesquitta, Walatta-Tseyon, Jung, Ho Sun, Moskvin, Oleg V., Thomson, James A., Slukvin, Igor I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066910/
https://www.ncbi.nlm.nih.gov/pubmed/29861167
http://dx.doi.org/10.1016/j.stemcr.2018.05.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066910/
https://www.ncbi.nlm.nih.gov/pubmed/29861167
http://dx.doi.org/10.1016/j.stemcr.2018.05.002

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