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Spatial organization of enzymes to enhance synthetic pathways in microbial chassis: a systematic review

For years, microbes have been widely applied as chassis in the construction of synthetic metabolic pathways. However, the lack of in vivo enzyme clustering of heterologous metabolic pathways in these organisms often results in low local concentrations of enzymes and substrates, leading to a low prod...

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Detalles Bibliográficos
Autores principales: Qiu, Xin-yuan, Xie, Si-Si, Min, Lu, Wu, Xiao-Min, Zhu, Lv-Yun, Zhu, Lingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066912/
https://www.ncbi.nlm.nih.gov/pubmed/30064437
http://dx.doi.org/10.1186/s12934-018-0965-0